Understanding Letrozole: Effects, Uses, and Considerations

Understanding Letrozole: Effects, Uses, and Considerations

Letrozole is an aromatase inhibitor primarily used in the treatment of breast cancer in postmenopausal women. It is prescribed to help lower estrogen levels in the body, which can slow the growth of hormone-sensitive tumors.

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How Letrozole Works

Letrozole functions by inhibiting the aromatase enzyme, which is responsible for converting androgen into estrogen in the body. By reducing estrogen production, Letrozole plays a crucial role in managing estrogen-receptor-positive breast cancers.

Benefits of Letrozole

1. Reduces Recurrence: Letrozole has been shown to significantly reduce the risk of cancer recurrence in hormone-positive breast cancer patients.
2. Improves Survival Rates: Clinical trials indicate that patients treated with Letrozole have improved survival rates compared to those on other therapies.
3. Treats Infertility: In some cases, Letrozole is used off-label to treat infertility in women with polycystic ovary syndrome (PCOS) by inducing ovulation.

Possible Side Effects

While Letrozole can be highly effective, it is important to discuss potential side effects with your healthcare provider. Common side effects may include:

• Hot flashes
• Joint pain
• Fatigue
• Bone density loss

Conclusion

Letrozole plays a significant role in the treatment of breast cancer and can be beneficial in certain reproductive health cases. However, as with any medication, it is essential to consult with your healthcare provider to ensure it is the right choice for your individual health needs.